Liver Bacterial Colonization in Patients with Obesity and Gut Dysbiosis.
Lucia PaianoManuela MastronardiGiuseppina CampiscianoNatalia RossoBiagio CasagrandaManola ComarNicolò de ManziniSilvia PalmisanoPublished in: Obesity surgery (2023)
To the best of our knowledge, this is the first study reporting the presence of bacterial genome in a liver biopsy on bariatric patients, instead of the microbe-associated molecular patterns. Notably, in literature, the presence of Roseburia intestinalis in stool samples has been shown to prevent intestinal inflammation playing its role in the gut barrier integrity. In our population, the Roseburia reduction was associated with the presence of bacterial genome in the liver, probably related to a greater permeability of the gut and vascular barriers.
Keyphrases
- end stage renal disease
- weight loss
- ejection fraction
- newly diagnosed
- systematic review
- chronic kidney disease
- healthcare
- oxidative stress
- metabolic syndrome
- insulin resistance
- type diabetes
- genome wide
- peritoneal dialysis
- emergency department
- roux en y gastric bypass
- body mass index
- bariatric surgery
- weight gain
- adipose tissue
- dna methylation
- patient reported outcomes
- high fat diet induced
- fine needle aspiration