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miR-126 promotes M1 to M2 macrophage phenotype switching via VEGFA and KLF4.

Xinyang ShouYimin WangQingyu JiangJun ChenQiang Liu
Published in: PeerJ (2023)
Our study shows that miR-126 can reverse ox-LDL-mediated phagocytosis and apoptosis in macrophages. Consequently, the potential role of miR-126 was manifested in regulating macrophage function and promoting vascular endothelial migration.
Keyphrases
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • adipose tissue
  • endoplasmic reticulum stress
  • endothelial cells
  • cell death
  • transcription factor
  • cell cycle arrest
  • signaling pathway
  • human health