Sex dimorphism in inflammatory response to obesity in childhood.
Estefania SimoesJoanna Correia-LimaLeonardo SardasFelipe StortiThais Zélia Dos Santos OtaniDaniel Augusto Correa VasquesVictor Henrique Oyamada OtaniPamela BertolazziCristiane KochiMarilia SeelaenderRicardo Riyoiti UchidaPublished in: International journal of obesity (2005) (2021)
Our data support a complex relationship between adiposity, blood cell count, and circulating inflammatory cytokine content. High SAA levels suggest that this factor may play a critical role in local and systemic inflammation. In the eutrophic group, females presented a lower status of inflammation, as compared to males. Both obese boys and girls showed an increased inflammatory response in relation to eutrophic counterparts. Taken together, results point out to clear sex dimorphism in the inflammatory profile of obese adolescents.
Keyphrases
- oxidative stress
- weight loss
- metabolic syndrome
- inflammatory response
- insulin resistance
- adipose tissue
- type diabetes
- physical activity
- weight gain
- bariatric surgery
- obese patients
- single cell
- lipopolysaccharide induced
- electronic health record
- stem cells
- cell therapy
- big data
- toll like receptor
- machine learning
- early life