Epilepsy in LAMA2-related muscular dystrophy: An electro-clinico-radiological characterization.

Daniel Natera-de BenitoJordi MuchartDebora ItzepCarlos OrtezLidia González-QueredaPía GallanoAlia RamirezJavier AparicioJana Domínguez-CarralLaura Carrera-GarcíaJessica Expósito-EscuderoNathalia Pardo CardozoDaniel CuadrasAnna CodinaCristina JouCecilia Jimenez-MallebreraFrancesc PalauJaume ColomerAlexis ArzimanoglouAndrés NascimentoVictoria San Antonio-Arce

Published in: Epilepsia (2020)

The epileptic phenotype of LAMA2-related MD is characterized by focal seizures with prominent visual and autonomic features associated with EEG abnormalities that predominate in the posterior quadrants. A consistent correlation between epileptic phenotype and neuroimaging was identified, suggesting that the extension of the polymicrogyria may serve as a predictor of epilepsy occurrence.

Keyphrases

muscular dystrophy
duchenne muscular dystrophy
risk assessment
heart rate variability
molecular dynamics
functional connectivity
temporal lobe epilepsy
blood pressure
resting state
high speed
high resolution