The 70-gene signature test as a prognostic and predictive biomarker in patients with invasive lobular breast cancer.

J Asher JenkinsSchelomo MarmorJane Yuet Ching HuiHeather BeckwithAnne H BlaesDavid PotterTodd M Tuttle

Published in: Breast cancer research and treatment (2021)

In this large database study, we found that the genomic risk category determined by the 70-gene ST was significantly associated with survival outcomes for patients with ILC. However, the 70-gene ST failed to predict the benefit of adjuvant chemotherapy for patients with high genomic risk.

Keyphrases

copy number
genome wide
genome wide identification
adverse drug
drug induced