Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis.

Emilie GueguenYasser MorsyCéline MamieAlain SchoepferCatherine SanerLuc BiedermannAlex StraumannAndrea Kreienbühlnull nullMichael Scharl Marcin Wawrzyniak

Published in: Gut (2024)

We identified a novel set of 53 dysregulated genes that are closely associated with the histological inflammatory activity of EoE. In combination with EDP, our new panel might be a valuable tool for the accurate diagnosis of patients with EoE as well as for monitoring their disease course.

Keyphrases

genome wide
single cell
oxidative stress
dna methylation
high resolution
rna seq
bioinformatics analysis
gene expression
chronic rhinosinusitis
genome wide identification
genome wide analysis