Epidermal growth factor receptor function in the human urothelium.
C WasénM EkstrandM LevinDaniel GiglioPublished in: International urology and nephrology (2018)
EGFr modulates urothelial proliferation and the formation of the three-dimensional structure of the urothelium possibly by interfering with occludin. The present data also show a cell culture technique enabling phenotypically normal urothelial cells to form epithelial structures in contrast to malignant urothelial cells.
Keyphrases
- epidermal growth factor receptor
- induced apoptosis
- tyrosine kinase
- high grade
- cell cycle arrest
- urinary tract
- endothelial cells
- small cell lung cancer
- advanced non small cell lung cancer
- signaling pathway
- cell death
- oxidative stress
- high resolution
- magnetic resonance imaging
- mass spectrometry
- big data
- cell proliferation