Evaluation of spoligotyping, SNPs and customised MIRU-VNTR combination for genotyping Mycobacterium tuberculosis clinical isolates in Madagascar.

Rondroarivelo RasoahanitralisoaNiaina RakotosamimananaDavid StuckiChristophe SolaSebastien GagneuxVoahangy Rasolofo Razanamparany

Published in: PloS one (2017)

According to the lineages and the spoligotype families, the number of MIRU-VNTR loci can be reduced to get an optimal classification of MTBC. These customized sets of MIRU-VNTR loci reduce workload and save resources while maintaining optimal discriminatory power.

Keyphrases

genome wide
mycobacterium tuberculosis
dna methylation
genome wide association
genome wide association study
machine learning
deep learning
high throughput
pulmonary tuberculosis
gene expression