Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer.
Rosario DistefanoLuisa TomaselloGian Luca Rampioni VinciguerraPierluigi GaspariniYujia XiangMarina BagnoliGioacchino P MarcecaPaola FaddaAlessandro LaganaMario AcunzoQin MaGiovanni NigitaCarlo M CrocePublished in: Cancer research (2022)
Modified miRNAs may act as cancer biomarkers and function as allies or antagonists of their canonical counterparts in gene regulation, suggesting the concurrent consideration of canonical and modified miRNAs can boost patient stratification.