Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer.

Rosario Distefano Luisa Tomasello Gian Luca Rampioni Vinciguerra Pierluigi Gasparini Yujia Xiang Marina Bagnoli Gioacchino P Marceca Paola Fadda Alessandro Lagana Mario Acunzo Qin Ma Giovanni Nigita Carlo M Croce

Published in: Cancer research (2022)

Modified miRNAs may act as cancer biomarkers and function as allies or antagonists of their canonical counterparts in gene regulation, suggesting the concurrent consideration of canonical and modified miRNAs can boost patient stratification.

Keyphrases

papillary thyroid
squamous cell
childhood cancer
squamous cell carcinoma
case report
young adults
rectal cancer