Serum Beta-Defensin-2 is a biomarker for psoriasis but not subclinical atherosclerosis: Role of IL17a, PI-3 kinase and Rac1.
C J PantojaH LiJ RodanteA KeelA V SorokinA SvedbomH L TeagueM StahleN N MehtaM P Playford
Published in: JEADV clinical practice (2023)
Our findings expand on the potential role of BD2 as a tractable biomarker in psoriasis patients and describes the role of an IL-17A-PI3-kinase/Rac signaling axis in regulating BD2 levels in keratinocytes.