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Diagnostic Yield of Ambulatory Reflux Monitoring Systems for Evaluation of Chronic Laryngeal Symptoms.

Amanda J KrauseMadeline GreytakAlexander M KaizerDustin A CarlsonWalter Wai-Yip ChanChien-Lin ChenChandra Prakash GyawaliAndrew JenkinsJohn E PandolfinoVinathi PolamrajuMing-Wun WongRena H Yadlapati
Published in: The American journal of gastroenterology (2023)
In this multicenter, international study of patients with chronic laryngeal symptoms referred for LPR evaluation, diagnostic yield of ambulatory reflux monitoring off acid suppression was 36% and rose to 50% when using wireless pH monitoring. In patients referred for chronic laryngeal symptoms, 24h pH-impedance monitoring may risk a low negative predictive value in patients with unproven GERD.
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