The effects of tumor resection and adjuvant therapy on the peripheral blood immune cell profile in patients with colon carcinoma.
Daniëlle KrijgsmanNatasja L De VriesMorten N AndersenAnni SkovboRob A E M TollenaarEsther BastiaannetPeter J K KuppenMarianne HoklandPublished in: Cancer immunology, immunotherapy : CII (2020)
Our results suggest tumor-induced suppression of NK- and NKT-like cells in CC patients, an effect that could not be detected after tumor resection. In contrast, adjuvant therapy maintained tumor-induced immunosuppression of NK- and NKT-like cells in CC patients.