Clinical and radiological outcomes of 5-year drug-free remission-steered treatment in patients with early arthritis: IMPROVED study.
Gülşah AkdemirLotte HeimansSytske Anne BergstraRobbert J GoekoopMaikel van OosterhoutJohannes H L M van GroenendaelAndré J PeetersGerda M Steup-BeekmanLeroy R LardPeter B J de SonnavilleBernard A M GrilletTom W J HuizingaCornelia F AllaartPublished in: Annals of the rheumatic diseases (2017)
Five years of DFR-steered treatment in patients with early RA resulted in almost normal functional ability without clinically relevant joint damage across treatment groups. Patients who achieved early remission had the best clinical outcomes. There were no differences between the randomisation arms. SDFR is a realistic treatment goal.