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Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement.

Jesper Guldsmed MadsenJakob Appel ØstergaardHenning AndersenMichael Pedersen
Published in: BioMed research international (2020)
Our findings showed that diabetes severely decreased the amplitude of cortical-evoked potentials and compromised the recuperation of motor neurons between activation. Conclusion/Interpretation. The reduced amplitude and weakened recuperation of diabetic motor neurons potentially may contribute to impaired transmission in motor pathways and thereby motor dysfunction.
Keyphrases
  • diabetic rats
  • oxidative stress
  • type diabetes
  • cardiovascular disease
  • spinal cord
  • glycemic control
  • resting state
  • risk assessment
  • metabolic syndrome
  • insulin resistance
  • drug induced
  • human health