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Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α-Synuclein.

Xiangyu TengAlena M ShevelevaFloriana TunaKeith Robert WillisonLiming Ying
Published in: Chemphyschem : a European journal of chemical physics and physical chemistry (2021)
The front cover artwork is provided by the group of Liming Ying at Imperial College London. The image shows that N-terminal acetylation of α-synuclein shifts the binding from the N-terminus to His50 and significantly slows down the binding reaction. Read the full text of the Article at 10.1002/cphc.202100651.
Keyphrases
  • histone deacetylase
  • dna binding
  • binding protein
  • aqueous solution
  • single molecule