Case report: hepatitis in a child infected with SARS-CoV-2 presenting toll-like receptor 7 Gln11Leu single nucleotide polymorphism.
Natália Lima PessoaAline Almeida BentesAndrea Lucchesi de CarvalhoThaís Bárbara de Souza SilvaPedro Augusto AlvesErik Vinicius de Sousa ReisTayse Andrade RodriguesErna Geessien KroonMarco Antônio CamposPublished in: Virology journal (2021)
To our knowledge, this is the first report of a SARS-CoV-2 caused hepatitis in a male child that has the tlr-7 Gln11Leu rs 179008, which could impair an efficient initial immune response. The knowledge of the patient's immune deficiency could improve the treatment to correct this deficiency with specific medications.