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Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees.

Huan LinGong ZhangXu-Chao ZhangXin-Lei LianWen-Zhao ZhongJian SuShi-Liang ChenYi-Long Wu
Published in: BMC cancer (2020)
The phenomenon that the enrichments of germline SNPs in the PI3K/AKT pathway might be a major predictor of familial susceptibility to lung cancer.
Keyphrases
  • dna repair
  • early onset
  • risk factors
  • gene expression
  • oxidative stress
  • dna methylation