Autoantibody profile in sarcoidosis, analysis from the GRADS sarcoidosis cohort.

Basheer Y KhassawnehChengsong ZhuBriana BarkesBrian VestalSarah ShrockMay GillespieKarin PachecoKevin D DeaneLisa A MaierQuan-Zhen LiNabeel Hamzehnull null

Published in: PloS one (2022)

Sarcoidosis patients have elevated IgM and IgG autoantibody levels compared to normal controls. In addition, individuals with pulmonary as well as additional organ involvement had higher IgM expression. Further research is needed focusing on specific organ-autoantibody pairs and role of autoantibodies in disease pathogenesis.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
peritoneal dialysis
systemic lupus erythematosus
prognostic factors
patient reported outcomes