Does inflammatory dental disease affect the development of medication-related osteonecrosis of the jaw in patients using high-dose bone-modifying agents?
Nobuhiro UedaChie NakashimaKumiko AokiHiroko ShimotsujiKazuhiko NakaueHajime YoshiokaSatoshi KurokawaYuichiro ImaiTadaaki KiritaPublished in: Clinical oral investigations (2020)
Our results suggest that the prophylactic extraction of teeth with radiopaque changes in bone surrounding the root before starting BMA therapy could prevent the onset of MRONJ.
Keyphrases
- high dose
- end stage renal disease
- bone mineral density
- ejection fraction
- newly diagnosed
- chronic kidney disease
- healthcare
- peritoneal dialysis
- low dose
- prognostic factors
- soft tissue
- oxidative stress
- emergency department
- bone loss
- stem cell transplantation
- oral health
- cell therapy
- smoking cessation
- replacement therapy