Tracking the time course of pathological patterns of lung injury in severe COVID-19.
Thais MauadAmaro Nunes Duarte-NetoLuiz Fernando Ferraz da SilvaEllen Pierre de OliveiraJose Mara de BritoEllen Caroline Toledo do NascimentoRenata Aparecida de Almeida MonteiroJuliana Carvalho FerreiraCarlos Roberto Ribeiro de CarvalhoPaulo Hilário do Nascimento SaldivaMarisa DolhnikoffPublished in: Respiratory research (2021)
Patients with severe COVID-19 present different proportions of DAD patterns over time, with advanced DAD being more prevalent after 17 days, which seems to be influenced by age and weight. Vascular involvement is present in a large proportion of patients, occurs early in disease progression, and does not change over time.