Influence of TMX2-CTNND1 polymorphism on cortical thickness in schizophrenia patients and unaffected siblings: an exploratory study based on target region sequencing.
Wenjian TanYixin ChengDanqing HuangDayi LiuJiamei ZhangJinyue LiZhening LiuYunzhi PanPublished in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) (2024)
This study identified regional morphological abnormalities in schizophrenia, including the right homologue of Broca's area, which was associated with a risk variant that affected delta-1 catenin and logical memory. These findings suggest a potential association between candidate gene loci, cortical thickness, and schizophrenia.
Keyphrases
- bipolar disorder
- end stage renal disease
- genome wide
- newly diagnosed
- ejection fraction
- optical coherence tomography
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- cell proliferation
- epithelial mesenchymal transition
- working memory
- single cell
- copy number
- patient reported outcomes
- gene expression
- risk assessment
- climate change
- autism spectrum disorder
- patient reported
- genome wide association study