Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials.
Rowan T ChlebowskiAaron K AragakiKathy PanReina HaqueThomas E RohanMihae SongJean Wactawski-WendeDorothy S LaneHolly R HarrisHoward StricklerAndrew M KauntizCarolyn D RunowiczPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
In randomized clinical trials, CEE-alone increased ovarian cancer incidence and ovarian cancer mortality, while CEE plus MPA did not. By contrast, CEE plus MPA significantly reduced endometrial cancer incidence.
Keyphrases
- endometrial cancer
- risk factors
- healthcare
- public health
- polycystic ovary syndrome
- mental health
- magnetic resonance
- quality improvement
- cardiovascular events
- health information
- computed tomography
- magnetic resonance imaging
- stem cells
- risk assessment
- adipose tissue
- pregnancy outcomes
- pregnant women
- metabolic syndrome
- social media
- insulin resistance
- young adults
- human health
- skeletal muscle
- bone marrow
- childhood cancer