COMT by DRD3 Epistatic Interaction in Modulating Behaviors in Children with ADHD: A Pharmaco-Dynamic Behavioral Approach.

Weam FageeraNatalie GrizenkoSarojini M SenguptaNorbert SchmitzRidha Joober

Published in: Journal of attention disorders (2020)

These findings suggest that COMT and DRD3 genetic variants may together play a role in ADHD symptomatology and response to treatment through gene-gene interaction.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
working memory
copy number
genome wide
genome wide identification
young adults
signaling pathway
dna methylation
gene expression