Genome-Wide and Transcriptome-Wide Association Studies on Northern New England and Ohio Amyotrophic Lateral Sclerosis Cohorts.

Siting Li Jiang GuiMichael N PassarelliAngeline S AndrewKathleen M SullivanKevin A CornellBryan J TraynorAli StarkRuth ChiaRebecca M KuenzlerErik P PioroWalter G BradleyElijah W Stommel

Published in: Neurology. Genetics (2024)

Our results support the need for future evaluation to clarify the role of these potential genetic risk factors for ALS and to understand genetic susceptibility to environmental risk factors.

Keyphrases

genome wide
amyotrophic lateral sclerosis
dna methylation
risk factors
copy number
human health
gene expression
risk assessment
single cell
climate change
case control