Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation.
Silje JohansenJostein KråkenesChristian A VedelerAnette Margrethe StorsteinHåkon ReikvamPublished in: Case reports in immunology (2022)
A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination revealed findings suspicious for limbic encephalitis (LE), successfully treated with intravenous immunoglobulins and intravenous corticosteroids. Although a rare complication after allo-HSCT, physicians should be aware of neurological symptoms that develop throughout the transplantation course.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- magnetic resonance imaging
- cerebrospinal fluid
- acute myeloid leukemia
- acute lymphoblastic leukemia
- sleep quality
- contrast enhanced
- high dose
- hematopoietic stem cell
- primary care
- computed tomography
- cell therapy
- diffusion weighted imaging
- single cell
- low dose
- magnetic resonance
- physical activity
- subarachnoid hemorrhage