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Predictive factors for response to neoadjuvant chemotherapy: inflammatory and immune markers in triple-negative breast cancer.

Hiroki KusamaNobuyoshi KittakaAi SomaAzusa TaniguchiHaruka KanaokaSatomi NakajimaYuri OyamaYukiko SetoJun OkunoNoriyuki WatanabeSaki MatsuiMinako NishioFumie FujisawaKeiichirou HonmaYasuhiro TamakiTakahiro Nakayama
Published in: Breast cancer (Tokyo, Japan) (2023)
TILs, NLR, and PLR predicted NAC efficacy against TNBC. TIL level was associated with NLR and PLR. NLR was an independent predictive factor and may be a useful surrogate marker for TILs when predicting pCR.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • lymph node
  • sentinel lymph node
  • transcription factor
  • oxidative stress
  • squamous cell carcinoma