Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining redox balance.
Kazeem Bidemi OkesinaAdeyemi Fatai OdetayoWale Johnson AdeyemiAyodeji Johnson AjibareAkeem Ayodeji OkesinaLuqman Aribidesi OlayakiPublished in: Laboratory animal research (2024)
Naringin prevented T2DM-induced testicular dysfunction by modulating XO/UA and restoring redox balance. Also, while the animals treated with OPE exhibited better ameliorative effects than their counterparts treated with naringin, the findings from this study showed that naringin would be a promising supplement for treating T2DM-induced male infertility.