Clinical presentation and outcome of human papillomavirus-positive nasopharyngeal carcinoma in a North American cohort.
Shao Hui HuangJ C Kennetth JacintoBrian O'SullivanJie SuJohn KimJolie RingashAnna SpreaficoEugene YuBayardo Perez-OrdonezIlan WeinrebJohn ChoAndrew J HopeScott V BratmanMeredith Elana GiulianiAli A HosniEzra HahnDavid P GoldsteinLi TongLawson EngWei XuJohn N WaldronPublished in: Cancer (2022)
HPV-positive NPC and EBV-positive NPC seem to be mutually exclusive diseases. Patients who have HPV-positive NPC have greater local symptom burden and larger primary tumors but have similar outcomes compared with patients who have EBV-positive NPC or HPV-positive OPC.