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Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain.

Emily J ShieldsMasato SoridaLihong ShengBogdan SieriebriennikovLong DingRoberto Bonasio
Published in: BMC biology (2021)
Our results demonstrate that Iso-Seq is an efficient and effective approach to improve genome annotations and maximize the amount of information that can be obtained from existing and future genomic datasets in Harpegnathos and other organisms.
Keyphrases
  • rna seq
  • single cell
  • gene expression
  • genome wide
  • dna methylation
  • copy number
  • white matter
  • current status
  • resting state
  • gram negative
  • multiple sclerosis
  • nucleic acid