A new steroidal saponin from the aerial parts of Solanum torvum.
Cuong Viet Canh LeNguyen Phuc Khanh NhiTran Phuong HaLe Tuan AnhTon That Huu DatPhung Thi Thuy OanhNguyen Thi Minh PhuongVo Thi Kim ThuDuc Viet HoHoang Le Tuan AnhPublished in: Natural product research (2021)
A new steroidal saponin, torvoside R (1), was isolated along with torvoside Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts of Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (1 - 3) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, and T24 cancer cell lines with IC50 values ranging from 14.18 to 89.31 µg/mL.