The Effects of Primary Unconjugated Bile Acids on Nanoencapsulated Pharmaceutical Formulation of Hydrophilic Drugs: Pharmacological Implications.
Armin MooranianThomas FosterCorina Mihaela IonescuLouise CareyDaniel WalkerMelissa JonesSusbin Raj WagleBozica KovacevicJacqueline ChesterEdan JohnstoneJafri KuthubutheenDaniel BrownMarcus D AtlasMomir MikovHani-Al SalamiPublished in: Drug design, development and therapy (2021)
CDCA-based metformin formulations exhibited improved stability and release profiles via thermal, chemical and electrokinetic effects, which were formulation-dependent suggesting potential applications of CDCA in the oral targeted delivery of hydrophilic drugs.