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A novel method to assess copy number variation in melanoma: Droplet digital PCR for precise quantitation of the RREB1 gene in FFPE melanocytic neoplasms, a proof-of-concept study.

Keegan O'HernRachael BarneyMeagan ChambersCatherine BakerMirjana StevanovicGregory J TsongalisEdward HughesAravindhan Sriharan
Published in: Journal of cutaneous pathology (2022)
Here we show that ddPCR can provide inexpensive, rapid, and robust data on the commonest copy number alteration in melanoma. Future development and validation could provide a useful ancillary tool in the diagnosis of challenging melanocytic lesions.
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