A metabolite-specific 3D stack-of-spiral bSSFP sequence for improved lactate imaging in hyperpolarized [1-13 C]pyruvate studies on a 3T clinical scanner.
Shuyu TangRobert BokHecong QinGalen ReedMark VanCriekingeRomelyn Delos SantosWilliam OverallJuan SantosJeremy GordonZhen Jane WangDaniel B VigneronPeder E Z LarsonPublished in: Magnetic resonance in medicine (2020)
Improved lactate imaging using the MS-3DSSFP sequence in hyperpolarized [1-13 C]pyruvate studies was demonstrated in animals and humans. The MS-3DSSFP sequence could be applied for other clinical applications such as in the brain or adapted for imaging other metabolites such as pyruvate and bicarbonate.