The relationship between sarcopenia detected in newly diagnosed colorectal cancer patients and FGF21, irisin and CRP levels.

Utku OflazogluSevinc CaglarHuriye Erbak YılmazHülya Tas ÖnalUmut VarolTarik SalmanYasar YildizSinan UnalZeynep Gulsum GucYuksel KucukzeybekAhmet AlacaciogluMustafa Oktay Tarhan

Published in: European geriatric medicine (2022)

This study was revealed that there is a negative relationship between sarcopenia and irisin and FGF-21 in operated non-metastatic colorectal cancer patients and there may be a relationship between sarcopenia and inflammation. It suggests that these biomarkers may play a role in the pathophysiology of sarcopenia. However, our results need to be validated in different types of cancer and with more patients.

Keyphrases

newly diagnosed
end stage renal disease
skeletal muscle
squamous cell carcinoma
small cell lung cancer
prognostic factors
oxidative stress
peritoneal dialysis
patient reported outcomes
community dwelling
single cell
young adults