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Human Plasma IgG N -Glycome Profiles Reveal a Proinflammatory Phenotype in Chronic Thromboembolic Pulmonary Hypertension.

Ze-Jian ZhangHui-Fang WangTian-Yu LianYu-Ping ZhouXi-Qi XuFan GuoYun-Peng WeiJing-Yi LiKai SunChao LiuLu-Rong PanMing RenLei NieHai-Long DaiZhi-Cheng Jing
Published in: Hypertension (Dallas, Tex. : 1979) (2023)
-glycome of a proinflammatory phenotype and the genes involved in its regulation in CTEPH. Plasma IgG galactosylation may be useful for evaluating the inflammatory state in patients with CTEPH; however, this requires further validation. This study improves our understanding of the mechanisms underlying chronic thromboembolic pulmonary hypertension inflammation from the perspective of glycomics.
Keyphrases
  • pulmonary hypertension
  • pulmonary artery
  • oxidative stress
  • pulmonary arterial hypertension
  • atrial fibrillation
  • single cell
  • gene expression
  • dna methylation