Progression of proliferative glomerulonephritis with monoclonal IgG deposits in pediatric patients.
Paul MillerAndrew Y XiaoVanderlene L KungRichard K SibleyJohn P HigginsNeeraja KambhamVivek CharuColin LenihanAmanda M UberElizabeth M TalleyNeiha AroraVighnesh WalavalkarZoltan G LaszikCynthia C NastMegan Leigh TroxellPublished in: Pediatric nephrology (Berlin, Germany) (2020)
Our study emphasizes the need for upfront IgG subclass investigation in pediatric mesangial or MPGN with IgG deposition and monotypic or biased light-chain staining. Furthermore, this pediatric experience suggests expanded pathogenic considerations in PGNMID. Graphical abstract.