The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.

Petter BjornstadSunita K SinghJanet K Snell-BergeonJulie A LovshinYuliya LytvynLeif E LovblomMarian J RewersGenevieve BouletVesta LaiJosephine TseLeslie ChamAndrej OrszagAlanna WeismanHillary A KeenanMichael H BrentNarinder PaulVera BrilBruce A PerkinsDavid Z I Cherney

Published in: Diabetes, obesity & metabolism (2018)

Elevated NGAL relates to intrarenal haemodynamic dysfunction in T1D, whereas elevated NGAL and B2M relate to intrarenal haemodynamic dysfunction in adults without T1D. These data may define a diabetes-specific interplay between tubular injury and intrarenal haemodynamic dysfunction.

Keyphrases

type diabetes
glycemic control
oxidative stress
cardiovascular disease
high glucose
electronic health record
machine learning
big data
skeletal muscle
endothelial cells
artificial intelligence