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Indication of activated senescence pathways in the temporal arteries of patients with giant cell arteritis.

William F JiemyYannick van SleenJacoba C GraverSarah PringleElisabeth BrouwerKornelis S M van der GeestDivi CornecAnnemieke M H BootsMaria Sandovici
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
Our data suggests the presence of activated senescence pathways at the site of vascular inflammation in GCA and support further research into the role of senescence in the pathophysiology of GCA. This article is protected by copyright. All rights reserved.
Keyphrases
  • giant cell
  • dna damage
  • endothelial cells
  • stress induced
  • oxidative stress
  • blood flow