Delivery of siRNA to Endothelial Cells In Vivo Using Lysine/Histidine Oligopeptide-Modified Poly(β-amino ester) Nanoparticles.

Pere DostaCatherine DemosVictor RamosDong Won KangSandeep KumarHanjoong JoSalvador Borrós

Published in: Cardiovascular engineering and technology (2021)

We demonstrate that C6-KH pBAE can used for delivery of siRNAs to the artery endothelium and lung, while minimizing potential side or toxic effects in the liver and heart.

Keyphrases

endothelial cells
heart failure
nitric oxide
atrial fibrillation
high glucose
amino acid
climate change
vascular endothelial growth factor
walled carbon nanotubes