Association of CD4+ Radiation-Induced Lymphocyte Apoptosis with Fibrosis and Telangiectasia after Radiotherapy in 272 Breast Cancer Patients with >10-Year Follow-up.
Marlon R VeldwijkPetra SeiboldAkke BotmaIrmgard HelmboldElena SperkFrank A GiordanoNicole GürthAnne KirchnerSabine BehrensFrederik WenzJenny Chang-ClaudeCarsten HerskindPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
The results provide first evidence that low CD4+ RILA is associated with increased subcutaneous fibrosis and telangiectasia even after 10 years. This supports the potential usefulness for predicting individual clinical risk.