Prognostic value and clinicopathological roles of phenotypes of tumour-associated macrophages in colorectal cancer.
Yamei ZhaoXiaoxu GeXiaoming XuShaojun YuJian WangLifeng SunPublished in: Journal of cancer research and clinical oncology (2019)
Unlike other solid tumours, high-density CD68+ macrophage infiltration can be a good prognostic marker for CRC. However, when macrophages act as targets of combination therapy in CRC treatment, this might be more effective for CRC patients with high CD8+ T cell infiltrate, NDM, MSI-H, NLNM and non-mucinous cancer.