The association between genotypes of urate transporter-1, Serum uric acid, and mortality in the community-based population: the Yamagata (Takahata) Study.

Soichiro KonTsuneo KontaKazunobu IchikawaMasafumi WatanabeHidenori SatoKenichi IshizawaYoshiyuki UenoHidetoshi YamashitaTakamasa Kayama

Published in: Clinical and experimental nephrology (2019)

This study revealed that the genetic predisposition of URAT1 was independently associated with mortality in the Japanese community-based population. This association might be due to the mechanism independent of serum uric acid levels.

Keyphrases

uric acid
metabolic syndrome
cardiovascular events
risk factors
gene expression
genome wide
type diabetes
dna methylation