A prospective pilot study of a gluten-free diet for primary sclerosing cholangitis and associated colitis.

Timur LiwinskiSina HübenerLara HenzePeter HuebenerMelina HeinemannMarcus TetzlaffMarie I HillerBettina JagemannRambabu SurabattulaDiana LeemingMorten KarsdalErika MonguzziGuido SchachschalThomas RöschCorinna BangAndre FrankeAnsgar W LohseDetlef SchuppanChristoph Schramm

Published in: Alimentary pharmacology & therapeutics (2022)

This study did not demonstrate a clinical improvement with short-term GFD in patients with PSC-IBD. However, a gluten/ATI-free diet may improve biomarkers of intestinal inflammation and barrier function in these patients with associated with changes in the enteric microbiota. Further investigation of the therapeutic potential of gluten-free diets in PSC-IBD is warranted.

Keyphrases

celiac disease
weight loss
ulcerative colitis
physical activity
irritable bowel syndrome