CHMP2A regulates broad immune cell-mediated antitumor activity in an immunocompetent in vivo head and neck squamous cell carcinoma model.
Jiyoung YunRobert Saddawi-KonefkaBenjamin GoldensonRiyam Al-MsariDavide BernareggiJaya L ThangarajShiqi TangSonam H PatelSarah M LunaJ Silvio GutkindDan S KaufmanPublished in: Journal for immunotherapy of cancer (2024)
Together, these studies demonstrate that CHMP2A is a targetable inhibitor of cellular antitumor immunity.
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