Subtyping CKD Patients by Consensus Clustering: The Chronic Renal Insufficiency Cohort (CRIC) Study.

Zihe Zheng Sushrut S WaikarInsa M SchmidtJ Richard LandisChi-Yuan HsuTariq ShafiHarold I FeldmanAmanda H AndersonFrancis Perry WilsonJing ChenHernan Rincon-CholesAna C RicardoGeorges SaabTamara IsakovaRadhakrishna KallemJeffrey C FinkPanduranga S RaoDawei XieWei Yangnull null

Published in: Journal of the American Society of Nephrology : JASN (2021)

Consensus clustering synthesized the patterns of baseline clinical and laboratory measures and revealed distinct CKD subgroups, which were associated with markedly different risks of important clinical outcomes. Further examination of patient subgroups and associated biomarkers may provide next steps toward precision medicine.

Keyphrases

chronic kidney disease
end stage renal disease
single cell

ejection fraction
newly diagnosed
rna seq

clinical practice
peritoneal dialysis
prognostic factors

case report
patient reported outcomes