Cross-reactive saliva IgA antibodies to oxidized LDL and periodontal pathogens in humans.
Ramin AkhiChunguang WangMikael KyrklundOuti KummuSini Pauliina TurunenKati HyvärinenArja KullaaTuula SaloPirkko J PussinenSohvi HörkköPublished in: Journal of clinical periodontology (2017)
Saliva contains IgA and IgG binding to oxLDL, which showed cross-reactive properties with the periodontal pathogens Porphyromonas gingivalis (P.g). The data suggest that secretory IgA to P.g may participate in immune reactions involved in LDL oxidation through molecular mimicry.