CHIPing Away at Proteomics to Find Correlations with Myeloid Neoplasms.

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

Plasma proteomic profiling to identify associations with myeloid neoplasm (MN) risk highlights the potential of integrating proteins and genetic biomarkers for the detection of individuals at high risk of developing MN. These proteins also offer valuable insights into biological pathways and inflammatory mechanisms involved in the progression of clonal hematopoiesis to MN. See related article by Tran et al., p. 3220.

Keyphrases

label free
room temperature
dendritic cells
bone marrow
transition metal
acute myeloid leukemia
metal organic framework
mass spectrometry
oxidative stress
low grade
single cell
genome wide
gene expression
human health
copy number
ionic liquid
drug induced