Relationships of BRAF V600E Gene Mutation With Some Immunohistochemical Markers and Recurrence Rate in Patients With Thyroid Carcinoma.
Tri Bui Dang MinhThuan Nghiem DucVan Phan Nguyen ThanhTuan Dinh LeMinh Tong DucTrung Nguyen HoangAnh Le TuanKien Xuan NguyenTien Tran VietThang Ba TaSon Tien NguyenHai Anh VuBa Van NguyenDung Nguyen Thi NgocViet Tran QuocThanh Bui DucPublished in: Clinical Medicine Insights. Oncology (2023)
A high prevalence of BRAF V600E gene mutation was found in thyroid carcinoma patients. The rates of positive HBME-1, COX-2, and Ki67 markers were significantly correlated to BRAF V600E gene mutation. Patients with BRAF V600E gene mutation showed a significantly higher relapse rate and earlier relapse time than those without the mutation.