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Ginkgetin Alleviates Intervertebral Disc Degeneration by Inhibiting Apoptosis, Inflammation, and Disturbance of Extracellular Matrix Synthesis and Catabolism via Inactivation of NLRP3 Inflammasome.

Baoshan HuShan LinShengrong LinGang Rui
Published in: Immunological investigations (2023)
GK suppressed apoptosis, inflammation, and ECM degradation to alleviate IDD via the inactivation of NLRP3 inflammasome.
Keyphrases
  • nlrp inflammasome
  • extracellular matrix
  • oxidative stress
  • endoplasmic reticulum stress
  • cell cycle arrest
  • cell death
  • signaling pathway
  • mouse model
  • pi k akt
  • cell proliferation