Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery.

Rene Billingwe AyisehGlory Enjong MbahElvis MonyaEmmanuel Menang NdiJudy SakanariSara LustigmanFidelis Cho-Ngwa

Published in: PLoS neglected tropical diseases (2023)

We have developed two immunocompetent small animal models for onchocerciasis and loiasis that can be used for microfilaricide discovery and to counter-screen onchocerciasis macrofilarides.

Keyphrases

high throughput
small molecule
single cell